Pharmaceutical industry material processing

Pharmaceutical Processing Equipment

 

Pharmaceutical processing and powder handling solutions

Pharmaceutical manufacturers need consistent material handling from incoming ingredients through finished blends. Product quality, operator protection and efficient batch production depend on equipment that is practical to clean, inspect and operate. For solid-dose, active pharmaceutical ingredient (API) and excipient manufacturers, each transfer and processing step must also support controlled product changeovers.

Akona Process Solutions brings together conveying, bulk material handling, sifting, screening, mixing and blending expertise to help manufacturers improve these operations. From individual equipment upgrades to connected processing systems, we help teams address production bottlenecks, reduce avoidable handling and develop a process that meets their material, cleaning and installation requirements.

Engineered solutions for pharmaceutical manufacturers

​Akona brings together Kason screening, Marion mixing and blending, and Spiroflow powder handling expertise. We can assess a standalone sanitary sifter or the connections between unloading, transfer, screening and blending, helping manufacturers resolve process restrictions without overlooking the cleaning work created at each interface.

Equipment selection begins with the intended process and the site’s requirements. Material trials can help assess separation, flow and product recovery, while design review establishes the access, connections and documentation required for the installation. The scope of qualification support and any containment performance requirements should be agreed for the selected equipment.

 

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Why pharmaceutical sanitary screening should start with the changeover

The purchase price of a pharmaceutical sieve is clear from the start. The time spent dismantling it, removing residues, inspecting components and preparing it for the next product can be less obvious, even though that work recurs throughout the equipment’s life. For manufacturers of solid-dose products and pharmaceutical ingredients, the screening decision therefore has consequences well beyond how fast powder passes through a mesh.

A machine may achieve the required separation during a batch yet remain difficult to manage between products. Restricted access, awkward seals, or powder retained at internal interfaces can prolong cleaning and make inspection harder. Sanitary screening offers a way to address these practical limitations while supporting the site’s cleaning-validation program. The opportunity is to recover useful manufacturing time through better equipment design and a more workable changeover.

end to end material processing solutions

Case Study

Pharmaceutical Material Processing with Sifters and Blenders

Akona supplies centrifugal sifters and blenders designed to handle pharmaceutical powders with care and precision. Our sifters support clean, efficient separation of fine materials, while our cone-style blenders ensure consistent, gentle mixing of active ingredients and excipients. Each system is built for sanitary performance, easy cleaning and reliable operation in regulated pharmaceutical environments.

Almac Pharma Services blending and centrifugal sifter equipment

Benefits Akona Brings to
the Pharmaceutical Industry

Validated systems for hygienic and compliant manufacturing.

Recover time at product changeover
A sanitary sifter that is easier to open, clean and reassemble can reduce the equipment-handling work between batches. Assess the complete interval through inspection and release to understand how improvements translate into available manufacturing time.

Reduce cross-contamination risk
Accessible product-contact surfaces and practical cleaning provisions help teams remove residues between products. The benefit depends on the selected design and the site’s cleaning procedure, supporting a controlled changeover rather than replacing cleaning validation.

Support consistent powder preparation
A pharma sifter selected for the material and separation duty helps control unwanted oversize or suitable agglomerates before downstream processing. Screening trials should assess product recovery and the condition of both accepted and rejected material.

Address the cost of quality
Repeat cleaning, investigations and delayed batches consume resources beyond the screening operation. Improving cleanability and inspection access can help reduce these sources of avoidable work, with the business case based on the site’s own changeover and quality records.

Pharmaceutical left image
Pharmaceutical left image